Pheochromocytoma manifeting hypertensive episodes, is a catecholamine-secreting neoplasm, arise from the chromaffin cells This clinical study was performed on 12 cases of pheocromocytoma treated surgically at the Department of Surgery of Chonnom
National University from January 1988 to June 1995.
@Es The results are as follows:
@EN 1) The male and female rate was 1: 2
The prevalent ages were the fifth decades(33%) and third, forth decades(25%).
2) The most frequent clinical symptoms and sings were hypertention and palpitation(83.3%), followed by headache, dispnea, faint and chest discomfort.
3) 41.7% of the patient presented clinical symptoms and signs less than 1 year of duration.
4) The 24-hour urine VMA was elevated in 100% of 10 cases. metanephrine was elevated in 77.8% of 9 cases.
5) Preoperative localization of tumor was easily acchieved by CT, US, MRI, 131-I MIBG scan, and angiography.
6) The alpha-adrenergic blocker was used preoperatively in 9 cases to control hypertension.
7) The tumor was located in the left adrenal gland in 6 cases(50%). Right adrenal gland in 5 cases(41.7%). Abdominal paragarglia in 1 cases(8.3%).
8) In pathologic and clinical findings, 4 cases were malignancy. Among them, 2 cases were recurred, mass excision was impossable in 1 case.
9) Post operative blood pressure was returned to normotensive level in 70%, post operative 24-hour urine VMA and metanephrine were found to be within normal level and significantly decresed in majority of the cases.
In conclusion, CT, US and MRI have good diagnostic results in preoperative localization of pheochromocytoma. And it is safe to operate pheochromocytoma with compatible preoperative preparation and it is important to close follow up with recurr or
metastasis in pathologically proven malignant pheochromocytoma.
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